ACTIVE PHARMACEUTICAL INGREDIENTS INTERMEDIATES
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INTERMEDIATES >>> 4-HYDROXY, 2-METHYL-2H-1,2-BENZOTHIAZINE CARBOXYLIC ACID METHYL ESTER-1,1-DIOXIDE(Intermediate of Meloxicam/Piroxicam)
 
Chemical Structure :
4-HYDROXY, 2-METHYL-2H-1,2-BENZOTHIAZINE CARBOXYLIC ACID METHYL ESTER-1,1-DIOXIDE(Intermediate of Meloxicam/Piroxicam)
Molecular Formula : C11H11NO5S
Molecular Weight : 269.0
Appearance : Off white crystalline powder
Solubility : Soluble in Chloroform
Melting Range : 160°C -166°C
Related Substance
By TLC
By HPLC
:
:
:

No secondary spot is seen
Not more than 1.0 % w/w
Water by KF : 0.5% max
Residual Solvent
By HS-GC
:
Methanol : 500 ppm max.
o-Xylene : 1000 ppm max.
DMF : 880 ppm max.
Assay(Dry basis) : Not less than 97% and not more than 101%
 
 
 
 
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