ACTIVE PHARMACEUTICAL INGREDIENTS INTERMEDIATES
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INTERMEDIATES >>> 4-HYDROXY, 2-METHYL-2H-1,2-BENZOTHIAZINE CARBOXYLIC ACID ISOPROPYL ESTER-1,1-DIOXIDE(Intermediat of Meloxicam/Piroxicam)
 
Chemical Structure :
4-HYDROXY, 2-METHYL-2H-1,2-BENZOTHIAZINE CARBOXYLIC ACID ISOPROPYL ESTER-1,1-DIOXIDE(Intermediat of Meloxicam/Piroxicam)
Molecular Formula : C13H15O5NS
Molecular Weight : 297
Appearance : Pinkish White Crystalline Powder
Solubility : Soluble in Methanol and Chloroform
Melting Range : 104°C -110°C
Related Substance
By TLC
By HPLC
:
:
:

No secondary spot is seen
Not more than 1.0 % w/w
Water by KF : 0.5% max
Residual Solvent
By HS-GC
:
Methanol : 500 ppm max.
o-Xylene : 1000 ppm max.
DMF : 880 ppm max.
Assay(Dry basis) : Not less than 97% and not more than 101%
 
 
 
 
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